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  2. Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system.
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  4. Cupid and Psyche system for the diagnosis and treatment of advanced cancer.
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    Yamashita T, Mizohata E, Nagatoishi S, Watanabe T, Nakakido M, Iwanari H, Mochizuki Y, Nakayama T, Kado Y, Yokota Y, Matsumura H, Kawamura T, Kodama T, Hamakubo T, Inoue T, Fujitani H, Tsumoto K.
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  6. Epiregulin-blocking antibody inhibits epiregulin-dependent EGFR signaling.
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  7. Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES.
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  8. The feasibility of an efficient drug design method with high-performance computers.
    Yamashita T, Ueda A, Mitsui T, Tomonaga A, Matsumoto S, Kodama T, Fujitani H.
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  9. Design and synthesis of biotin analogues reversibly binding with streptavidin.
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    Chem Asian J. 2015 Apr;10(4):1071-8. doi: 10.1002/asia.201500120. Epub 2015 Mar 5.
  10. Structure-based design of a streptavidin mutant specific for an artificial biotin analogue.
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  11. Structure-based design and synthesis of a bivalent iminobiotin analog showing strong affinity toward a low immunogenic streptavidin mutant.
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  12. Crystal structure of streptavidin mutant with low immunogenicity.
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  13. Molecular dynamics simulation-based evaluation of the binding free energies of computationally designed drug candidates: importance of the dynamical effects.
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  14. Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies.
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